GWS star Jeremy Cameron will front the AFL tribunal and is set to receive a long suspension for the heavy clash that left Brisbane defender Harris Andrews with bleeding on his brain.
As expected, match reviewer Michael Christian will let Tuesday night's tribunal hearing decide Cameron's fate.
He can expect to be banned for at least four games.
Carlton veteran Dale Thomas was also offered a one-game ban for rough conduct.
Cameron and Andrews clashed in a marking contest on Saturday, with Christian grading the incident as intentional conduct, severe impact and high contact.
Regardless of whether Cameron intended to hurt Andrews, Christian said the Giants forward could have better protected his opponent.
"Everything was considered with determining the conduct," Christian told reporters on Monday.
"When it's all said and done, the provisions are pretty clear that a raised forearm or elbow is usually conclusive that a strike is intentional, and that's the way we decided to grade it."
Andrews spent Saturday night in hospital and the Lions said on Monday that he is being monitored for brain bleeding, but is expected to make a full recovery.
Brisbane's medical report will be another factor counting against Cameron at the tribunal hearing.
With Andrews sidelined for the majority of the game, GWS went on to win by 27 points.
The incident has prompted a fresh round of debate about whether the AFL should introduce a send-off rule to prevent teams from being disadvantaged in such scenarios.
AFL legend Leigh Matthews on Monday said with the technology now available to officials, there was a case to be made for send-offs.
"It would be much fairer to the game that is being played that if the guy who knocked the other bloke out, he also got removed from the game," he told Macquarie Sports Radio.
Christian declined to weigh in on the topic.
"I think the system that we've got is very good," he said.
"I think there's lots of talk and documentation around the pros and cons of that but it's something I wouldn't like to get into right now."
Thomas is the only other player facing suspension, for an incident involving Collingwood opponent Levi Greenwood.
There was speculation North Melbourne's Brownlow Medal fancy Shaun Higgins might be in suspension trouble, but he was offered a $2000 fine for misconduct against the Western Bulldogs' Josh Dunkley.
It was a busy day for Christian, with 15 charges laid.